How to deal with Corruption in Monster Train 2

Corruption deals 1 damage per stack at the end of every turn and, unlike Frostbite or Decay, its stacks never decrease. No Monster Train 2 clan has a card that removes debuffs, so the answer is to stop it being applied: Mute the source, Daze or Sap the attacker, or let a disposable unit take the hits. A Damage Shield absorbs the whole Corruption tick, however many stacks there are.

Enemies that apply it and what stops them

Enemy	How it Corrupts	What works
Misshapen Fiend	Explodes when it dies and Corrupts your front unit, even if killed before combat	Mute or a Zone of Silence room; otherwise let a spare unit in front take it. Sap and Daze do nothing.
Blightbound Guardian	Corruption on Strike	Sap 2 stops its attack; Daze; Quick damage kills it first
Deformed Duo	The most Corruption per Strike, plus Reanimate	Multi-hit spells, Multistrike sweepers or Decay to strip Reanimate; Daze or Mute
Qel the Corruptor	Incant: each spell you cast on his floor gives your units Corruption 3. From Covenant 4, his Summon gives all your units Corruption 5	Mute only. Cast few spells on his floor; units played after he arrives avoid the Summon hit, so hold unit cards.
Seraph Aeternus-The Dominant	Action: Corruption 2 to your units; his Strike doubles the target’s Corruption	Daze (stops the Action and the Strike), Mute, a high-Health blocker, or Ascend/Descend him away from your main floor
Dominion (Titans fight)	Resolve: Corruption 5 to your front unit on every floor	Sap 2 stops his Pyre hits; rotate front units

The only Mute in the clans

Madame Lionsmane on the Maneater path has Maneating III at tier III: cooldown 1, Sap 4, Decay 15 and Mute 2 on one unit. PesNRen’s guide names it as the one clan source of Mute that works on Qel and Seraph. A Zone of Silence room (Clanless) Silences non-boss enemies on its floor, which stops Misshapen Fiend explosions there but not Qel or Seraph.

Seraph the Dominant

His waves are full of Misshapen Fiends, Blightbound Guardians and Deformed Duos, and from Covenant 2 the first wave alone has three Fiends. Plan for it from the start of the run:

• Give backline units enough Health, healing or Armor to absorb small Corruption ticks for the whole fight.
• Keep a blocker in front of the units that matter. It takes the Fiend explosions and Seraph’s doubling Strike.
• Daze is the strongest single answer, because it stops both his Action and his Strike.
• Sap rarely works on him: his 20 Attack needs 10 stacks to reach 0.

PesNRen rates Banished and Luna Coven as the two clans with the hardest matchup against this Seraph.