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Guides Alchemy

Alchemy recipes and rune alternatives

Updated for Steam update 1.011

Alchemy uses the ingredient’s red, green and blue rune totals. Study an ingredient to reveal its rune values, then match the required total at the Laboratory. Different ingredients can make the same product.

Peat alone and Berry plus Blood both give one green and one blue rune for Dream Dust.
Two ingredient routes to the same Dream Dust rune total. Original diagram.

Use the alchemy reference and ingredient solver to compare 29 rune formulas and search the included reagents under Laboratory I or II’s slot limit. The Reanimation Liquid route separates its three-slot mixture from corpse preparation, while Organ Improvers explains treatment after brewing.

Useful rune recipes

Laboratory I has two ingredient slots; Laboratory II has three. Slot count limits how you assemble the runes, even if the desired total is otherwise correct.

Product Red Green Blue Laboratory
Paint 0 2 0 I
Lacquer 0 0 2 I
Dream Dust 0 1 1 I
Preservative 0 3 0 I
Organ Improver, white skull 0 4 0 I
Organ Improver, red skull 4 1 0 I
Reanimation Liquid 2 1 4 II

Discovered recipes appear in the Folio, the open book at the top of the room.

Compare the shortest rune mixtures for all 29 formulas, including the difference between occupied slots and distinct ingredients.

Choose ingredients you can replace

For Dream Dust, Peat alone supplies 1 green and 1 blue. A Berry plus Blood supplies the same total in two slots. Peat is useful when you want to conserve Blood, but a low compost supply may make the other route more convenient.

For Paint, Flour supplies 2 green in one slot. For Lacquer, Minced Meat or a Night Flower supplies 2 blue. Two Blood also total 2 blue, using both slots of Laboratory I. Use the spare-slot requirement to decide between routes before gathering more ingredients.

For the white-skull Organ Improver, two Flour provide 4 green. For the red-skull version, Stone gives 2 red and Copper Nugget gives 2 red plus 1 green, producing the required 4 red and 1 green in two slots.

These are ingredient alternatives with the same rune totals, not claims that gathering them takes the same time. A recipe using a rare ingredient can be worse for your current stockpile than one using two common items.

Organ treatment is a separate step

Mixing an Organ Improver produces the potion. Upgrading the organ then happens at the Formulation Bench, using the organ and the appropriate improver. Making a white-skull potion in the Laboratory does not directly change a body on an Autopsy Table.

Use white-skull treatment for a burial candidate and red-skull treatment for a worker whose collar supports the result. Keep the ingredient route separate from the anatomy operation so the wrong potion is not spent on the wrong body.

Sources

  1. hekitakai: alchemy recipes and ingredient testsRune costs, ingredient alternatives, laboratory slots and the Folio.
  2. Formulation Bench organ and reagent referenceOrgan Improver recipes use the Laboratory before organ treatment at the Formulation Bench.
  3. magnipotence: lessons from a completed playthroughResurrection preparation, stockpile routing, full storage and town population scrolls.

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