Best weapons by area and for each boss

Damage type matters more than raw Power: most enemies and many bosses take extra damage from Slash, Pierce or Impact, and the bestiary shows the weakness after your first kill. Carry one main weapon of each type, swap when a fight shows its weakness, and level the one you will keep, since each weapon level adds 3% damage.

The two loadouts that come up most often across the guides:

Use	Three main weapons	Why
General fighting, from the Tower of Knowledge on	Jigeki’s Serpent Thrust, Splash Hammer, Vampiric Scimitar	Pierce with a poison stun, Impact with an area special, and Slash that heals on normal hits
Long boss fights	Spiked Buckler, Vampiric Scimitar, Diamond Blade	Parry and counter, healing, and the highest listed Power (16)

The Vampiric Scimitar is in both: games.gg ranks it first and builds around it, and Gamerblurb puts it in its hard-fight set. Keep Holy Sword Endu or Soul Bound Endu in a slot while exploring; its Wind Dash works without it equipped, but the sword’s own secondary dash does not.

By area

Power and Speed are the in-game values listed by fan guides, given where published.

Area	Weapon: Power, Speed, type	Where	Use it for
Isle of Neasied	Rusted Spear: 5, Fast, Pierce	Chest in the broken tower above the first Crystal Monument	Main weapon; its backward-dash stab keeps you out of reach. Evolves at level 10 into Jigeki’s Serpent Thrust (11, Fast)
Isle of Neasied	Wooden Club: 10, Slow, Impact	Crypt, chest right of the Forest Eye room	Skeletons and the Shrine Guardian, both weak to Impact
Isle of Neasied	Throwing Dagger: Physical	Rope on the second islet off the beach	Forest Eyes, diamond switches, chip damage between boss swings
Umbada’s shop	Cestus: 8, Very Fast, Impact	20 coins	Its uppercut doubles as an extra jump to ledges
Obmuer Temple	Splash Hammer: 15, Slow, Impact	Shrine chest in the waterfall cavern with the Royal Orbewa Guards	The area special clears Dagoom’s Toxic Serfs
Obmuer Temple	Piercing Needle: Pierce	Chest after the Sacred Cistern	Hits several enemies in a line; Erda and Wami are weak to Pierce
After Dagoom (Silver Duck)	Diamond Blade: 16, Slow, Slash/Impact. Spiked Buckler: 13, Average, Impact/Pierce	Umbada, 25 and 33 coins	Heavy single hits; parry and counter
Tower of Knowledge	Azure Torch: Azure Flame	Gargoyle statue at the tower entrance	A recharging fireball for fights you cannot take in melee; also lights the beacons
Tower of Knowledge	Occult Knife: Physical	Entrance Hall chest	Homing throw for the floating Necronomicon
Tower of Knowledge	Paralysis needles: paralysis	Forbidden Archives chest; Umbada sells their upgrade	Players call paralysis the strongest boss tool
After the Necronomicon (Golden Duck)	Vampiric Scimitar: 10, Average, Slash. Occult Warhammer: 12, Average, Impact	Umbada, 42 and 30 coins	Healing on hit; two recharging hammer throws
After the Necronomicon	Skull Rod: 8, Fast, Impact	Top of the Forbidden Archives	A recharging ranged attack
Deimpo Mausoleum	Grave Reaper: 14, Slow, Slash. Blood Moon: 15, Slow, Impact	Crumbling Staircase chests	Grave Reaper builds six boomerang charges from hits
Deimpo Mausoleum	Rusted Greataxe: Slash+Impact	Hanging building on the Crumbling Staircase	Evolves at level 10 into a weapon that fires a piercing blue flame wave
Ancient World	Explorer’s Cudgel: Impact. Heavy Rifle: ancient gun	Ossi’s ten-module quest; Umbada late stock	Clearing groups; a grenade secondary that a Data Module upgrades
Siraatsu Castle	Iron Fist: Physical	Foyer area, chest on an iron-grating platform past the lift	Straight splash shots; see the patch note below
Endgame	True Holy Sword Akunra: 17, Average, Slash. Okbujo’s Judgement: Slash	Altar of Purification; Deimpo hidden altar	Required for Endings 2 to 4, so they must win the queen fight

Skip the Pandora Blade as a damage weapon: it starts at Power 5, never evolves, and a level-100 copy with +300% still deals about 20 per hit.

Against each boss

Weaknesses are the bestiary values; “none” means the bestiary lists no physical weakness, so bring your highest-level weapon.

Boss	Weak to	Bring
Shrine Guardian	Impact	Wooden Club, Throwing Daggers
Royal Orbewa Guards	Erda and Wami: Pierce. Yepo: none	Rusted Spear or Serpent Thrust; Piercing Needle
Dagoom the Sea King	None	Splash Hammer for the Toxic Serfs, Azure Torch if you have it, every throwable, Roasted Ojum Lizards
The Necronomicon	Book: none. Flesh forms: Impact (Baphomet), Slash (Eye of Balor), Pierce (Bael)	Occult Knife and daggers for the book; one main weapon of each type for the forms
Poenir and Duenir	None	Throwables for Poenir in the air, a fast weapon for short openings
Castle Lords	Duke Obetda: Slash. Duchess Ubhaer: Impact	Vampiric Scimitar or Diamond Blade, plus an Impact weapon
Dekanima Ritual of Blood	Ritual Blood Tauropod: Impact. Ritual Blood Stalker: Pierce	Impact and Pierce
High Spec Automatons	Drilling Unit X: Pierce. Besom Cutter Pro: Slash	Pierce and Slash
Josami Lord Saijha, Queen Siraatsu	None	A ranged option for the laser and unsafe patterns; for the queen, the ending weapon

The castle’s three encounters together need all three damage types, so enter with one main weapon of each. Fight-by-fight patterns are in the hardest bosses guide.

Late-game picks and 1.01.06

• Iron Fist: players called it the strongest gun before 1.01.06, able to kill bosses in three shots. After the 12 November patch two players read its upgraded Power as 18 instead of 25. The official notes list only a fix for weapons that mixed up their secondary attacks, so whether this was intended is unconfirmed. Energy weapons run dry quickly, so keep a melee weapon in the next slot.
• Azure Torch and Skull Rod: the early ranged pair several players kept into the mid game because both recharge while equipped.
• Throwing set in the late game: one player pairs Okbujo’s Judgement with Royal Throwing Daggers (last chest of Puwema’s Lounge), Okbujo’s Gaze (hidden door on 4F of the Peak Vestibule) and High Performance Blades (Ventilation Shaft).
• Grimoire weapons: writing a code in the Witch’s Grimoire gives weapons such as Hempie’s SVT 38, a 10-round gun that gains 3% per level up to level 25. Players who used it describe it as breaking the game’s balance.

Levelling for damage

Pick the weapon you will keep before you level it: rusted weapons and Endu restart at level 1 when they evolve, and Ossi’s Data Module upgrades need level 10. Spear first is the usual order, because Serpent Thrust’s Poison Strike (poison and a stun of about one second) carries through the mid game. Farming spots and Spirit Oil are in weapon levels and evolution.